Random effects model fit to the natural anti-RhD titer decline of donors in the absence of boostering.

Abstract

<p>A jitter of 1.75 was applied to the titer change measurements to enhance interpretability of the data. For individual fits, the line ends at a donor’s maximum time of measurement. Note that for 5% of donors a small positive annual change is modelled due to measurement errors and since it is not possible to restrict the model to negative values.</p