Metabolic benefits of HBG barley flour are abolished under GF conditions.

Abstract

<p>Fecal short chain fatty acids in germ-free and conventional mice were measured by GC/MS (A). Body weight changes (B), fat mass (C), plasma PYY (D), and GLP-1 levels (E) were measured in male germ-free mice fed a Co or HBG diets for 12 weeks. Daily food intakes were measured at 8 to 10 weeks of age (F). Values are means ± S.E.M. n = 5. **, <i>P</i> < 0.01, compared with Co (Tukey-Kramer test for A) (student’s t-test for B-F). Co, Control; Conv-Co, Conventional mice fed a Co diet; Epi, epididymal; GF-Co, Germ-Free mice fed a Co; GF-HBG, Germ-Free mice fed a HBG; GLP-1, glucagon-like peptide 1; HBG, β-glucan rich barley; Peri, perirenal; PYY, peptide YY; Sub, subcutaneous; WAT, white adipose tissue.</p

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