In this thesis we investigate the effects of the physical constraints such as antenna aperture size, antenna geometry and non-isotropic scattering distribution parameters (angle of arrival/departure and angular spread) on the performance of coherent and non-coherent space-time coded wireless communication systems. First, we derive analytical expressions for the exact pairwise error probability (PEP) and PEP upper-bound of coherent and non-coherent space-time coded systems operating over spatially correlated fading channels using a moment-generating function-based approach. These analytical expressions account for antenna spacing, antenna geometries and scattering distribution models. Using these new PEP expressions, the degree of the effect of antenna spacing, antenna geometry and angular spread is quantified on the diversity advantage (robustness) given by a space-time code. It is shown that the number of antennas that can be employed in a fixed antenna aperture without diminishing the diversity advantage of a space-time code is determined by the size of the antenna aperture, antenna geometry and the richness of the scattering environment. ¶ In realistic channel environments the performance of space-time coded multiple-input multiple output (MIMO) systems is significantly reduced due to non-ideal antenna placement and non-isotropic scattering. In this thesis, by exploiting the spatial dimension of a MIMO channel we introduce the novel use of linear spatial precoding (or power-loading) based on fixed and known parameters of MIMO channels to ameliorate the effects of non-ideal antenna placement on the performance of coherent and non-coherent space-time codes. ..