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Development and Micro Manufacturing of Coronary Stents in Hungary

Abstract

Revascularisation by endovascular implant (stent) has great importance in the treatment of coronary artery diseases. Stents are high-technology implants that are the creation of the knowledge of health sciences, physics, chemistry, material science and engineering. Its development can be carried out only by the involvement of these areas of knowledge. Hungary has a stent production since 1995, which is the only one in the new EU member countries. The aim of the project that has been started within the frameworks of the National Research and Development Program, is the development of a new stent family based on the results of the material science researches have started for 10 years and the clinical and production experiences of experts, which could result an equivalent Hungarian product to the market leader products in case of several product lines. The original wire-mesh cut for those replaced welded stents made of wire later from tubes laser cutted ones. The stents are made of biocompatible materials: 316LVM stainless steel, Co-Cr alloys and nitinol. Stents made from wires are produced by weaving, or reeling and resistance projection welding. Nowadays, stents are produced mostly by high-precision laser cutting. These were large steps forward in the development of production technology, following the appearance of balloon catheters. Independently of what kind of manufacturing process is used, it has to be very precise because a connecting goal of the development is to increase the biocompatibility of the stents with surface treatment and to create a coating that is able to carry drug on the smooth surface. The paper presents the antecedents, achievements and main future objectives in micro manufacturing speciality of that special medical device, that is just before the surface treatment and coating process of the stent

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