Surface
functionalization of nanoparticles and host–guest
properties of nanoassemblies are two critical features in the utilization
of nanostructures in a variety of applications in materials, chemical,
and biological nanotechnology. However, simultaneously incorporating
these two features in one nanoparticle design is a rather challenging
task. We have developed a simple and versatile nanoparticle platform
that addresses this challenge. We have designed and characterized
a polymer nanoparticle that provides the ability to encapsulate hydrophobic
guest molecules and surface functionalization with a wide range of
functional groups. In addition, we have also demonstrated a new and
simple approach to tune the size of the nanoparticles