With regard to increasing the fish meal price, utilization of hygienic and analyzed poultry by product meal as an alternative protein source in diets for Huso huso within growth period were investigated. Six test diets isonitrogenous and isocaleric (contain 42% protein and 20 Mj kg-1 energy) were prepared. Fish meal was substituted by poultry by product at 20% (PBM20), 40% (PBM40), 60% (PBM60), 80% (PBM80) and 100% (PBM100) in base diet, respectively. A total of 180 Huso huso with average (±SD) weight of 107.89±5.9gr were stocked in 18 fiberglass tanks (Voloum:2000 lit,Temperature:20±2C 0) and fed satiation to 18 weeks. No significant differences were detected between final weight (FW),weight gain (WG) and specific growth rate of fish fed (PBM0), (PBM20), (PBM40), (PBM60) and (PBM80) respectively. The Highest protein belonged to fish fed PBM20 (%16.97±0.36) with significant difference with PBM40 (% 15.41 ± 0.67), respectively. Body lipid fish fed PBM80 and PBM100 (%6.63±0.016) (%7.49±0.17) were significantly lower than other treatments. The Synchronic hepatosomatic index increased with increasing poultry by product in diets and highest rate were found in fish fed PBM 100 , but except PBM20, visceral index in fish fed other treatments was same. The result showed that up to 80% fish meal could be replaced by poultry by product with no adverse effect on growth and feed conversion ratio for Huso huso within growth period
