The aim of this research is to determine the levels of polycholoro biphenil (PCBs) in skin and muscle tissues of common carp (Cyprinus carpio) and common pike (Esox lucius) fishes in the west part of Anzali wetland (Abkenar) in the two seasons, autumn 2009 and winter 2010. In each seasons, nine fishes from each species were selected randomly. The samples, transferred in cool condition and the muscles and skins of them were removed. All of the preparations organs clean up and PCBS analysis were carried with GC-ECD (Gas chromatography). Mean concentrations of PCBS were 24.36пg/g dry.w in skin 14.36пg/g dry.w in muscle tissue for E. lucius and 21.84пg/g dry.w in skin and 20.86пg/g dry.w in muscle tissue of C. carpio. In the autumn, the values was less than FDI standard and food standard Australia/AZ MRL and skin tissue of E. lucius and muscle tissue of C. carpio was over of US EPA standard values. Mean concentration of PCBS were 29.43пg/g dry.w in skin and 10.10ng/g dry.w in muscle tissue for E. lucius and 33.06пg/g dry.w in skin and 11.00пg/g dry.w in muscle tissue for C. carpio. In the winter, the value was less than FDI standard and food standard Australia /AZ MRL and skin tissue of E. lucius and skin tissue of C. carpio was over of US EPA standard values. Mean concentration of PCBs in water in the autumn (0.0042ppb) was less than recommended water quality Criteria E.P.A and in the winter (0.1938ppb) was over recommended water quality Criteria E.P.A. Mean concentration of PCBs in sediment in the autumn (4.89ng/g dry.w) and winter (4.48ng/g dry.w) was less than Interim Canadian Sediment Quality Guidelines. There were significant differences between E. lucius mussels and C. carpio skin tissue in two seasons (autumn and winter) in water and ingredient suspension. But in sediments, no significant difference was detected in autumn and winter
