The Obří důl Fe-Cu-As sulfide deposit is hosted in metamorphosed lenses of marble, calc-silicate rocks and skarns. The deposit is located up to a few hundred meters away from the contact of the large, late-orogenic Variscan Krkonoše-Jizera Plutonic Complex (KJPC). Mineralogical and fluid inclusion studies of the Gustavská ore lens show that the main sulfide stage, dominated by pyrrhotite, chalcopyrite and arsenopyrite, originated from water-rich hydrothermal fluids with salinities up to 8 wt.% NaCl eq. at temperatures ranging from 324 to 358°C.These fluids replaced mainly the carbonate-rich lithologies. The 34S values indicate a magmatic source of sulfur and Re/Os dating of molybdenite are consistent with simultaneous formation of the main sulfide stage ore and the KJPC