Cover Photo Credit: Camerique
IN THIS ISSUE:
2 The Declaration of Dependence, General Superintendent: William M. Greathouse
3 When Push Comes to Shove, John W. May
4 Letters
5 What Do I Have in My Hand?, D. W. Hildie
6 Promises (a Poem), Alice Hansche Mortenson
6 A Shattered Man Finds Freedom, Anonymous
8 Safe Isn’t the Same as Right, David F. Nixon
9 Confession, not Concealment, Freeman T. Hodgins
10 A Humble Man Exalted, Bruce Banks
11 Chaplains and Changed Lives, Mark E. Farris
12 The “Skunk Sweater”, Linda Hudspeth Loetscher
13 Security (a Poem), Charles Cunningham
14 God Still Heals, Richard S. Taylor
15 The Test (a Poem), Nina Beegle
15 Two Miracles for Rita, Nora Brush
16 Circle Vision Evangelism, Barbara H. Taylor
17 His Victory and Ours: The Temptations of Jesus, Reuben Welch
18 The Editor’s Standpoint, W. E. McCumber
20 By All Means, Edith Holcomb
21 In the News
30 News of Religion
31 Answer Corner
35 Late Newshttps://digitalcommons.olivet.edu/cotn_hoh/1162/thumbnail.jp

Driessens, Marc

Famaey, J.P.

Orloff, S.

Chochrad, I.

Cleppe, D.

de Brabanter, G.

Ginsberg, F.

Mindlin, A.

Soenen, M.

Cover Photo Credit: Mabel P. Adamson
IN THIS ISSUE:
2 Biblical Discipleship, General Superintendent: Charles H. Strickland
3 The Nazarene Bible College Experience, Earl B. Wheeler
4 Letters
5 Where Women Prepare for Ministry, Verla Oke Lambert
6 God is the Reason We Are Here, Phyllis H. Perkins
7 Filled Up, Poured Out (a Poem), E. Ruth Glover
7 “Because You Gave…”, Robert Hempel
8 From the “Ivory Tower” to the “Grass Roots”, Floyd E. Perkins
9 Nazarene Roots: Theology for Life and Ministry
10 The Evolution of Trimble Library, Roger M. Williams
11 Education with a Purpose for Ministry, Ross W. Hayslip
12 Wesley on Child Rearing?, William H. Bray
13 He’s Yours, Lord; Please Heal Him or Take Him Home, Joseph Harshman
14 Stewardship: All or Nothing, Gary Allen Henecke
15 O, Guard My Lips!, Alice Hansche Mortenson
15 Milestones and Landmarks, Gene Van Note, Editor
16 The Editor’s Standpoint, W. E. McCumber
18 Choose Your Attitude, Carlton D. Hansen
19 Restitution, Harold L. Bowlby
20 By All Means, Frank Dizmang
21 In the News
30 News of Religion
31 Answer Corner
35 Late Newshttps://digitalcommons.olivet.edu/cotn_hoh/1167/thumbnail.jp

McCumber, W. E., (Editor)

Digital Commons @ Olivet

English

Herald of Holiness Volume 76 Number 18 (1987)

Olivet Nazarene University

Abstract: This was a double-blind, parallel-group, multiple-dose study designed to compare the efficacy and tolerability of the sustained-release (SR) formulations of ibuprofen and diclofenac sodium for patients suffering from chronic back pain. The patients were randomly allocated to treatment with either the recommended once-daily dosage of ibuprofen SR (1600 mg) or diclofenac SR (100 mg) for 14 days; 30 patients were treated with ibuprofen and 32 with diclofenac. Clinical assessments of the patients' back condition were made at the beginning and end of the study, and the patients themselves rated their quality of sleep, level of activity, and severity of pain each day. In terms of efficacy, the ibuprofen SR treatment resulted in a trend toward better patient responses for all variables other than quality of sleep and night pain, although differences between the two treatment groups were not statistically significant. There were eight patient withdrawals in the diclofenac SR group (six due to adverse events) compared with four patients in the ibuprofen SR group (only one attributed to adverse events). Overall, 16 diclofenac SR-treated patients reported 24 adverse events, 8 of which were recorded as definitely related to the drug. Four ibuprofen SR-treated patients reported a total of nine adverse events, and only three were considered to be definitely drug related. The difference between the groups in the number of patients reporting adverse events was statistically significant (P = 0.002). The demonstrated efficacy and superior tolerability of ibuprofen SR provide strong support for the use of this once-daily formulation in the management of patients with chronic back pain

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