Figure S3. Viperin is not needed for the induction of ISGs in cortical neurons and astrocytes. Primary WT and viperin−/− mouse cortical neurons and astrocytes were treated with 5000 U/mL IFNαB/D for 16 h or left untreated. mRNA expression of Mx1, IFIT1, and CXCL10 was determined by qPCR. Expression levels were normalized to the endogenous GAPDH expression and depicted as mRNA arbitrary units (AU). (PDF 531 kb