Tering of OC spheroids following treatment with all used drugs (cisplatin, topotecan and paclitaxel (taxol)), that discriminates between compact spheroids and aggregates. A subset of candidate genes were initially obtained by filtering on signal intensity (2-fold), retaining 527 genes. One-way ANOVA parametric test (Welch -test, variances not assumed equal, ≤ 0.03) further selected 85 genes. Clustering analysis based on the 85 gene list was performed using the standard Condition Tree algorithm provided in GeneSpring. The mean appears , whereas signifies up-regulation, and signifies down-regulation (see legend bar). Compact spheroids are indicated in , aggregates are indicated in . Each cell line is indicated with different color.<p><b>Copyright information:</b></p><p>Taken from "Global gene expression analysis of early response to chemotherapy treatment in ovarian cancer spheroids"</p><p>http://www.biomedcentral.com/1471-2164/9/99</p><p>BMC Genomics 2008;9():99-99.</p><p>Published online 26 Feb 2008</p><p>PMCID:PMC2279123.</p><p></p
