This study concerns a thermodynamic and technical optimization of a small scale Organic Rankine Cycle system for waste heat
recovery applications. An Artificial Neural Network (ANN) has been used to develop a thermodynamic model to be used for
the maximization of the production of power while keeping the size of the heat exchangers and hence the cost of the plant at its
minimum. R1234yf has been selected as the working fluid. The results show that the use of ANN is promising in solving complex
nonlinear optimization problems that arise in the field of thermodynamics