Clinical evaluation of blood pressure lowering, endothelial function improving, hypolipidemic and anti‐inflammatory effects of pomegranate juice in hypertensive sub
Abstract Pomegranate (Punica granatum L.) juice (PJ) contains different types of
antioxidants and bioactive polyphenols and has been reported to promote cardiovascular
health through several mechanisms. The present study aimed to examine the effects of 2-
week intake of fresh PJ on blood pressure, flow-mediated dilatation (FMD), serum lipid
profile and concentrations of inflammatory and endothelial function biomarkers. Twenty-one
hypertensive patients (aged 30–67 years) were recruited into the trial and assigned to
receive either PJ (150 ml/day in a single occasion between lunch and dinner; n= 11) or the
same amount of water (n= 10) for a period of 2 weeks. Systolic (SBP) and diastolic (DBP)
pressures together with FMD and serum concentrations of lipid profile parameters,
apolipoproteins A and B, intracellular adhesion molecule-1 (ICAM-1), vascular..
