<p>Distribution of distances (in nt) for 568 cases where a predicted σ<sup>70</sup>-promoter (genome-wide search, p-values<10<sup>−4</sup>) and a TSS were found in proximity (≤60 nt) of each other. TSSs are divided into 5 groups (A, B, C, D, E) defined by the differences between the means of signal intensities upstream and downstream of the TSS. The 5 groups are the inter-percentile ranges (E: 0–20%, D: 21–40%, C:41–60%, B: 61–80%, A: 81–100%) of the ranked mean differences (see Methods). At distances above 40 nt the observed number of co-localized TSSs and promoters (≤10 counts) is equal to the expected number co-localized TSSs and promoters (see Methods).</p
