Representative photomicrograph of the expected morphology of the urinary bladder in a cross-section

Abstract

<p><b>Copyright information:</b></p><p>Taken from "Transcription factor network downstream of protease activated receptors (PARs) modulating mouse bladder inflammation"</p><p>http://www.biomedcentral.com/1471-2172/8/17</p><p>BMC Immunology 2007;8():17-17.</p><p>Published online 17 Aug 2007</p><p>PMCID:PMC2000913.</p><p></p> Figure 5A is a composite of 18 H&E stained photomicrographs of the same cross-section at original magnification of 100× and illustrates the localization of the different layers: urothelium and submucosa, as well as the detrusor muscle. Black wavy line indicates the urothelium/submucosal layer. Figure 5B is a high magnification of the mouse bladder urothelium showing a multi-layered urothelium with apical umbrella cells (yellow arrow)