Stereoview of C2′- and C1′- AAF-dG structures, superimposed on the base and AAF moiety

Abstract

<p><b>Copyright information:</b></p><p>Taken from "A new conformation for -(deoxyguanosin-8-yl)-2-acetylaminofluorene (AAF-dG) allows Watson–Crick pairing in the P2 DNA polymerase IV (Dpo4)"</p><p>Nucleic Acids Research 2006;34(3):785-795.</p><p>Published online 1 Feb 2006</p><p>PMCID:PMC1360743.</p><p>© The Author 2006. Published by Oxford University Press. All rights reserved</p> The C1′- AAF-dG is taken from the last snapshot of the 1-AAF-dG:-dCTP trajectory ( = 120.4°). The C2′- AAF-dG ( = 162.0 °) differs from the C1′- AAF-dG only in the sugar pucker pseudorotation angle, (,). Other torsions are χ = 201.8°, α′ = 101.0°, β′ = 30.7° and γ′ = 33.6°. The nucleotides are colored by atom with the AAF moiety shown in red and the methyl of the acetyl group in cyan. For clarity hydrogen atoms are not shown. Collision is denoted by the red circle