<p><b>Copyright information:</b></p><p>Taken from "c-Jun N-terminal kinase (JNK) cooperates with Gsk3β to regulate Dishevelled-mediated microtubule stability"</p><p>http://www.biomedcentral.com/1471-2121/8/27</p><p>BMC Cell Biology 2007;8():27-27.</p><p>Published online 3 Jul 2007</p><p>PMCID:PMC1940000.</p><p></p>of endogenous JNK activity, when compared to controls. Low levels of Anisomicin also increase the level of p-c-Jun when compared with control untreated EGFP-expressing neurons or neurons exposed to β-estradiol for three hrs. However, the levels of total c-Jun remain unchanged. Quantification of three independent experiments shows that induction of Dvl-ER expression induces a 40% increase in p-c-Jun levels compare to control. Expression of Dvl increases the level of p-JNK decorating the MT network along neurites when compared to EGFP-expressing control neurons. Pseudocolor panels show Dvl increases the level of p-JNK associated with microtubules. Scale bar 5 μm. Two asterisks, < 0.01
