Sequence and structure of the -acting genomic HDV ribozyme used in this study

Abstract

<p><b>Copyright information:</b></p><p>Taken from "The genomic HDV ribozyme utilizes a previously unnoticed U-turn motif to accomplish fast site-specific catalysis"</p><p></p><p>Nucleic Acids Research 2007;35(6):1933-1946.</p><p>Published online 2 Mar 2007</p><p>PMCID:PMC1874588.</p><p>© 2007 The Author(s)</p> () Secondary structure of the genomic HDV ribozyme with the set of 5′-sequences (green) immediately upstream of the cleavage site (open arrow) as employed in our cleavage and footprinting experiments. Nucleotides in color correspond to important structural elements in the catalytic core. Red dashed lines, functionally relevant tertiary interactions. () Secondary structure of the truncated sequence used in our MD simulations, color coded as in (A). () Backbone ribbon representation of the precursor crystal structure (), color-coded as in (A and B)