Model of the secretory pathway under different ER stress conditions (t-PA secretion, tunicamycin and DTT) together with examples of genes that are transcriptionally induced or repressed
<p><b>Copyright information:</b></p><p>Taken from "Genomic analysis of the secretion stress response in the enzyme-producing cell factory "</p><p>BMC Genomics 2007;8():158-158.</p><p>Published online 11 Jun 2007</p><p>PMCID:PMC1894978.</p><p></p> The gene designation is provided where previously known or, otherwise, the gene name is provided. Red, genes up-regulated by 3 conditions; orange, genes up-regulated by 2 conditions; yellow, genes up-regulated by 1 condition; light blue, genes down-regulated by 1 condition; blue, genes down-regulated by 2 conditions. N, nucleus; ER, endoplasmic reticulum; E, endosome; V, vacuole; G, Golgi. ERAD is ER-associated degradation
