Main molecular targets of curcumin divided in biological action (apoptosis, cell proliferation, antioxidant response, inflammatory response)

Abstract

<p><b>Copyright information:</b></p><p>Taken from "Curcumin in Cell Death Processes: A Challenge for CAM of Age-Related Pathologies"</p><p></p><p>Evidence-based Complementary and Alternative Medicine 2007;4(2):181-190.</p><p>Published online 23 Apr 2007</p><p>PMCID:PMC1876609.</p><p>© 2007 The Author(s)</p> Orange arrows indicate enhancement, blue lines indicate inhibition. Circles group molecules involved in the indicated processes (aging, cancer, neurodegeneration). DFF40: CAD DNA endonuclease; IAP: Inhibitor of Apoptosis Protein family; GPx: Glutathione Peroxidase; mTOR: mammalian Target Of Rapamycin; A-β: beta-amyloid; iNOS: inducible Nitric Oxide Synthase