Changes in cell membrane potential induced by D-glucose, thioglycosides I and VII (10

Abstract

<p><b>Copyright information:</b></p><p>Taken from "Thioglycosides as inhibitors of hSGLT1 and hSGLT2: Potential therapeutic agents for the control of hyperglycemia in diabetes"</p><p></p><p>International Journal of Medical Sciences 2007;4(3):131-139.</p><p>Published online 5 May 2007</p><p>PMCID:PMC1868657.</p><p>© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.</p> Blue and red bars represent hSGLT1 and hSGLT2, respectively. The change in FRET signal was normalized to the values obtained from non-transfected CHO cells (controls). Results are the mean of six different experiments. Error bars represents standard deviations. * < 0.01 shows significantly higher induction of cell membrane depolarization in treated cells as compared to control cells (not exposed to thioglycosides)