Abstract

<p><b>Copyright information:</b></p><p>Taken from "Atrazine-Induced Aromatase Expression Is SF-1 Dependent: Implications for Endocrine Disruption in Wildlife and Reproductive Cancers in Humans"</p><p></p><p>Environmental Health Perspectives 2007;115(5):720-727.</p><p>Published online 5 Feb 2007</p><p>PMCID:PMC1867956.</p><p>This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original DOI</p> () Atrazine and simazine stimulated ArPII in H295R cells without exogenous SF-1 supplementation. () ArPII response to atrazine and simazine in NIH-3T3 cells required coexpression of SF1. () Atrazine and simazine stimulation of SF-1–mediated ArPII in SF-1–co-transfected NIH-3T3 cells was dose dependent. Both triazines were effective at concentrations as low as 10 mol/L (ANOVA, < 0.05). Bars show mean ± SD; letters above bars indicate statistical groups (ANOVA, < 0.05)

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