Loss of TRAIL expression pattern in oral leukoplakia with severe dysplasia

Abstract

<p><b>Copyright information:</b></p><p>Taken from "Repression of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) but not its receptors during oral cancer progression"</p><p>http://www.biomedcentral.com/1471-2407/7/108</p><p>BMC Cancer 2007;7():108-108.</p><p>Published online 25 Jun 2007</p><p>PMCID:PMC1924860.</p><p></p> A: Hematoxylin and eosin staining (× 100); B: Immunohistochemical staining for TRAIL (× 100). Note that TRAIL expression is mostly lost in dysplastic epithelium (arrow). In contrast, mononuclear immune cell infiltrate (MNC) associated with dysplasia reveals intense staining for TRAIL