Echinus does not require deubiquitinating activity to promote normal IOC death

Abstract

<p><b>Copyright information:</b></p><p>Taken from ", required for interommatidial cell sorting and cell death in the pupal retina, encodes a protein with homology to ubiquitin-specific proteases"</p><p>http://www.biomedcentral.com/1471-213X/7/82</p><p>BMC Developmental Biology 2007;7():82-82.</p><p>Published online 5 Jul 2007</p><p>PMCID:PMC1950886.</p><p></p> (A-D) SEMs of adult eyes of various genotypes. (E-H) Pupal retinas of various genotypes stained with anti-Dlg. (A,E) GMR-driven expression of a microRNA targeting ec-SF1 results in an echinus phenotype. (B,F) eyes. (C,G) Eyes of genotype ; GMR-ec-SF2/+. (D,H) Eyes of genotype ; GMR-ec-SF3/+. Expression of versions of Echinus that lack essential USP catalytic residues rescues the phenotype