Tramiprosate, a drug of potential interest for the treatment of Alzheimer's disease, promotes an abnormal aggregation of tau-1

Abstract

<p><b>Copyright information:</b></p><p>Taken from "Tramiprosate, a drug of potential interest for the treatment of Alzheimer's disease, promotes an abnormal aggregation of tau"</p><p>http://www.molecularneurodegeneration.com/content/2/1/17</p><p>Molecular Neurodegeneration 2007;2():17-17.</p><p>Published online 6 Sep 2007</p><p>PMCID:PMC2048960.</p><p></p>ab T14) (A) or with 0.01 % thioflavin S (Th-S) (B). Quantitation of both T14 (C) and Thioflavin S (D) fluorescence observed by fluorescence microscopy is shown. The fluorescence intensity of each sample was obtained by background subtraction. A significant fluorescence intesity increase (P < 0.05 as compared with untreated cells) is shown for both T14 and Thioflavin S staining. The average of at least three separate determinations is indicated. DAPI was used for nuclei staining

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