Unintegrated HIV-1 provides an inducible and functional reservoir in untreated and highly active antiretroviral therapy-treated patients-6

Abstract

<p><b>Copyright information:</b></p><p>Taken from "Unintegrated HIV-1 provides an inducible and functional reservoir in untreated and highly active antiretroviral therapy-treated patients"</p><p>http://www.retrovirology.com/content/4/1/60</p><p>Retrovirology 2007;4():60-60.</p><p>Published online 29 Aug 2007</p><p>PMCID:PMC2048509.</p><p></p>HIV-1 integrase inhibitor L-731,988 at the final concentration of 40 μM. . To assess the correlation between the unintegrated HIV-1 DNA decay and the decline of rescuable viral production, infected resting CD4T cells were preincubated 1 or 2 days before polyclonal stimulation. In both cases, in order to prevent infection of others cells by -synthesized HIV-1, 1 μg/ml of the viral entry inhibitor T20 was also added in culture medium