<p><b>Copyright information:</b></p><p>Taken from "Distinct roles of and in the development of rhythmic neural networks controlling inspiratory depth, respiratory frequency, and jaw opening"</p><p>http://www.neuraldevelopment.com/content/2/1/19</p><p>Neural Development 2007;2():19-19.</p><p>Published online 26 Sep 2007</p><p>PMCID:PMC2098766.</p><p></p> Plethsymographic recordings of wild-type (top), and heterozygous (middle) and homozygous (bottom) mutant mice at P0. Inspiration is upward. Note that in mice, there is a two-fold increase in tidal volume compared with and wild-type littermates, whereas the frequency is the same (about 110 breaths/minute). Individual data relating tidal volume (V, abscissa) and number (nb) of jaw openings (ordinates) at P0.1. Each symbol corresponds to one animal. Black triangles are for mutants (b, c), open circles represent mutants (c) and open squares correspond to wild-type animals (b). Note that mutants can be separated from other genotypes at P0.1, due to their two-fold increased tidal volume and their reduced number of jaw openings. Broken lines indicate the values used to calculate penetrance of the phenotype (V, all data inferior to mean – 1 standard deviation; jaw openings, all data superior to mean + 1 standard deviation)
