Fc gamma receptor (FcγR) expression correlates with the presence of T cells in rheumatoid arthritis (RA) synovium

Abstract

<p><b>Copyright information:</b></p><p>Taken from "High synovial expression of the inhibitory FcγRIIb in rheumatoid arthritis"</p><p>http://arthritis-research.com/content/9/3/R51</p><p>Arthritis Research & Therapy 2007;9(3):R51-R51.</p><p>Published online 23 May 2007</p><p>PMCID:PMC2206344.</p><p></p> Sequentially sectioned synovial tissue from a late stage RA patient demonstrating FcγRI, II and III positive cells perivasculary. The FcγR positive cells are located in the same area as CD3 positive T cells. Note the FcγRIII positive cell inside the vessel. This staining was representative of all other late RA synovial tissues stained in the same way (= 26). The IgG1 isotype control did not show any background (data not shown). (Original magnification ×250.) The expression of FcγRI, II and III was significantly correlated with the expression of CD3 in RA synovium (each symbol represents one patient, = 26)

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