<p><b>Copyright information:</b></p><p>Taken from "Platelet-derived growth factor receptor-β, carrying the activating mutation D849N, accelerates the establishment of B16 melanoma"</p><p>http://www.biomedcentral.com/1471-2407/7/224</p><p>BMC Cancer 2007;7():224-224.</p><p>Published online 12 Dec 2007</p><p>PMCID:PMC2234427.</p><p></p>e subcutaneously injected on both sides of the midline of the lower dorsal abdomen of wild type (wt) or D849N-mutant mice (mut). Six tumors were analyzed for each experimental combination. When the B16 melanomas had reached 0.8 cm, they were removed and analyzed for ratio of total vessel area/viable tumor (A), average vessel surface (B), number of vessels per high-power field (C) and numerical density of pericytes per perimeter of vessel (D). Asterisks indicate statistical significance (*, p < 0.05; **, p < 0.01; ***, p < 0.001; ****, p < 0.0001) by Student's -test
