<p><b>Copyright information:</b></p><p>Taken from "Epidermal growth factor receptor structural alterations in gastric cancer"</p><p>http://www.biomedcentral.com/1471-2407/8/10</p><p>BMC Cancer 2008;8():10-10.</p><p>Published online 16 Jan 2008</p><p>PMCID:PMC2244615.</p><p></p>ain of EGFR – missense mutation (2300 C>T) in exon 20, leading to the substitution of the Alanine 767 for a Valine. (B) Diffuse gastric carcinoma with EGFR increased copy number caused by chromosome 7 polysomy. (C) Neoplastic cells exhibiting gene amplification with the formation of clusters with numerous signals for EGFR
