<p><b>Copyright information:</b></p><p>Taken from "Broad network-based predictability of gene loss-of-function phenotypes"</p><p>http://genomebiology.com/2007/8/12/R258</p><p>Genome Biology 2007;8(12):R258-R258.</p><p>Published online 5 Dec 2007</p><p>PMCID:PMC2246260.</p><p></p> Thus, there does not appear to be an intrinsic limitation for applying network-guided reverse genetics even when seed set size is small. Each filled circle indicates the prediction strength (area under the receiver operating characteristic [ROC] curve, as calculated in Figure 3) of one of the 100 loss-of-function phenotypes relative to the number of genes in that seed set
