Human immunodeficiency virus integrase inhibitors efficiently suppress feline immunodeficiency virus replication and provide a rationale to redesign antiretroviral treatment for feline AIDS-4

Abstract

<p><b>Copyright information:</b></p><p>Taken from "Human immunodeficiency virus integrase inhibitors efficiently suppress feline immunodeficiency virus replication and provide a rationale to redesign antiretroviral treatment for feline AIDS"</p><p>http://www.retrovirology.com/content/4/1/79</p><p>Retrovirology 2007;4():79-79.</p><p>Published online 30 Oct 2007</p><p>PMCID:PMC2244644.</p><p></p>ion was quantified by measuring p25 core antigen release in cell culture supernatants. Drug efficacy was assessed as percent decrease in p25 concentrations. Data points represent an average from three independent experiments following appropriate transformations to restore linearity. The solid line is the line best fitting the data points; the dashed curves represent the 95% confidence limits. The ECvalues (reported in the main text) were calculated by transposing onto a linear scale the intersection of the regression line (and 95% confidence limits) with the dotted line corresponding to 50% inhibition of viral replication

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