Dystrophin deficiency in canine X-linked muscular dystrophy in Japan (CXMD) alters myosin heavy chain expression profiles in the diaphragm more markedly than in the tibialis cranialis muscle-6
<p><b>Copyright information:</b></p><p>Taken from "Dystrophin deficiency in canine X-linked muscular dystrophy in Japan (CXMD) alters myosin heavy chain expression profiles in the diaphragm more markedly than in the tibialis cranialis muscle"</p><p>http://www.biomedcentral.com/1471-2474/9/1</p><p>BMC Musculoskeletal Disorders 2008;9():1-1.</p><p>Published online 9 Jan 2008</p><p>PMCID:PMC2257929.</p><p></p>otein were separated on 8% SDS-polyacrylamide gels containing 30% glycerol. Four MHC isoforms (I, IIX, IIA, and embryonic) were detected. NTC: normal TC muscle at 1 year old. Note that MHC type I increased in the affected diaphragm after 6 months old. (B) Quantitative analysis of MHC isoforms. MHC expression between two groups (normal affected) or among ages (1, 2, 4, 6 months and 1 year) was analyzed by Yates's chi-square test. Significant differences (< 0.05) were detected between normal and affected groups in TC muscles after 2 months old or in diaphragms after 4 months old, and between 1 and 2 months old in normal TC muscles
