Human umbilical vein endothelial cells (HUVECs) were pretreated with AKT inhibitor-IV (1 μM) or MEK1/2 inhibitor PD98059 (10 μM) for 4 h, followed by treatment with EGCG (40 μM) for 2 h
Cells were harvested and TUNEL assay was performed as per manufacturer's instructions (Promega). Data represent mean ± SD. * = significantly different from control, P < 0.05.<p><b>Copyright information:</b></p><p>Taken from "Inhibition of PI3K/AKT and MEK/ERK pathways act synergistically to enhance antiangiogenic effects of EGCG through activation of FOXO transcription factor"</p><p>http://www.jmolecularsignaling.com/content/3/1/7</p><p>Journal of Molecular Signaling 2008;3():7-7.</p><p>Published online 20 Mar 2008</p><p>PMCID:PMC2278143.</p><p></p
