The blot also compares periaxin in control (Con) and –null cells (CRE) infected with GFP control adenovirus (GFP) or a Krox-20/GFP virus (K20). Note high periaxin levels in Krox-20–infected –null cells (CRE). (B–E) control ( con) and –null mouse Schwann cells 2 d after infection with Krox-20/GFP adenovirus. Note that Krox-20 induces much higher levels of P protein in –null cells (D and E) than in control cells (B and C). The reason why P levels in the Krox-20–expressing control cells appear low in this picture (C) compared with other comparable experiments (e.g., ) is that exposure had to be reduced (equally for C and E) to avoid overexposure in E. (F and G) P protein expression in control cells P ( con) and c–null mouse Schwann cells after 3 d of exposure to db-cAMP/NRG-1. Note that cAMP/NRG-1 induces substantially higher P levels in cells without c-Jun. Bars, 15 μm.<p><b>Copyright information:</b></p><p>Taken from "c-Jun is a negative regulator of myelination"</p><p></p><p>The Journal of Cell Biology 2008;181(4):625-637.</p><p>Published online 19 May 2008</p><p>PMCID:PMC2386103.</p><p></p
