Mitochondrial DNA heteroplasmy in ovine fetuses and sheep cloned by somatic cell nuclear transfer-0

Abstract

Tings from an alignment of concatenated mtDNA sequences (3806 nucleotides: control region, , , and ) of the three donor cell lines, their SCNT clones (CA1 to CA7, CB1 to CB3, and CC1 and CC2) and of an European mitochondrial reference genome (GenBank:). The scale bar represents 0.001 substitutions per site, and quartet puzzling values are shown (all are >50). The numbers at the nodes (quartet puzzling values) indicate the frequencies of occurrence for 1,000 replicate trees. Quartet puzzling support values provide an estimate of support of a given branch and can be interpreted in much the same way as bootstrap values. CA5 is the most divergent donor A-derived clone which is highlighted by the ellipse (see below for amino acid changes).<p><b>Copyright information:</b></p><p>Taken from "Mitochondrial DNA heteroplasmy in ovine fetuses and sheep cloned by somatic cell nuclear transfer"</p><p>http://www.biomedcentral.com/1471-213X/7/141</p><p>BMC Developmental Biology 2007;7():141-141.</p><p>Published online 21 Dec 2007</p><p>PMCID:PMC2323970.</p><p></p

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