Non-cell autonomous impairment of oligodendrocyte differentiation precedes CNS degeneration in the Zitter rat: Implications of macrophage/microglial activation in the pathogenesis-4

Abstract

And rats. Insets show ferritin-positive cells in the substantia nigra reticulata. , Confocal images of double labeling for Rip and ferritin in the substantia nigra, showing the increased expression of ferritin in Rip-positive oligodendrocytes (). The diffuse immunoreactivity of ferritin was often observed around the Rip-positive oligodendrocytic processes (). Panels and represent pairs of double stained photomicrographs. Scale bars: 10 μm (A-D); 500 μm (E, F); 10 μm (insets in E, F); 10 μm (G-H'). , cerebellar white matter.<p><b>Copyright information:</b></p><p>Taken from "Non-cell autonomous impairment of oligodendrocyte differentiation precedes CNS degeneration in the Zitter rat: Implications of macrophage/microglial activation in the pathogenesis"</p><p>http://www.biomedcentral.com/1471-2202/9/35</p><p>BMC Neuroscience 2008;9():35-35.</p><p>Published online 5 Apr 2008</p><p>PMCID:PMC2323389.</p><p></p

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