Ect was blocked by caffeine at the dose of 3 mg/day. Caffeine alone had no effect on extravasation of IgG in normal rabbit brain. Representative images taken from 2 rabbits in each group with 6 sections from each animal are shown. Bar = 50 μm. (B) Cholesterol-enriched diet significantly increased accumulation of IgG in olfactory bulb and this effect was blocked by caffeine at the dose of 3 mg/day. (C) Neither cholesterol-enriched diet nor caffeine changed significantly plasma levels of IgG. n = 4, *p < 0.05.<p><b>Copyright information:</b></p><p>Taken from "Caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer's disease"</p><p>http://www.jneuroinflammation.com/content/5/1/12</p><p>Journal of Neuroinflammation 2008;5():12-12.</p><p>Published online 3 Apr 2008</p><p>PMCID:PMC2330033.</p><p></p
