Detection of activator protein 2 alpha (AP-2α), Yin Yang 1 (YY1), and ERBB2 by immunohistochemistry in breast tumors

Abstract

Case with low immunoreactivity for AP-2α. Tumor sample expressing high level of AP-2α protein in more than 80% of the nuclei.Tumor with low immunoreactivity for YY1. Case expressing high level of YY1 protein in more than 80% of the nuclei. Case with no ERBB2 membrane staining, scored as IHC 0. Tumor with partial weak membrane staining, scored as IHC 1+. Case with ERBB2 score of 2+. Tumor with thick circumferential ERBB2 membrane staining, scored as IHC 3+.<p><b>Copyright information:</b></p><p>Taken from "The combined immunodetection of AP-2α and YY1 transcription factors is associated with gene overexpression in primary breast tumors"</p><p>http://breast-cancer-research.com/content/10/1/R9</p><p>Breast Cancer Research : BCR 2008;10(1):R9-R9.</p><p>Published online 24 Jan 2008</p><p>PMCID:PMC2374961.</p><p></p

    Similar works

    Full text

    thumbnail-image

    Available Versions