Msi1 interacts with the 3′ UTR of its target mRNA and PABP, and subsequently inhibits translation initiation by competing with eIF4G for PABP

Abstract

These sequential events inhibit formation of the 80S ribosome complex.<p><b>Copyright information:</b></p><p>Taken from "Neural RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP"</p><p></p><p>The Journal of Cell Biology 2008;181(4):639-653.</p><p>Published online 19 May 2008</p><p>PMCID:PMC2386104.</p><p></p