From a parent with allele (without mutation) or a parent with allele (with an to mutation); an offspring with allele can be derived from a parent with allele (without mutation) or a parent with allele (with an to mutation). B) In the presence of recombination, an offspring with allele at locus can be derived from parent(s) in the previous generation by four pathways: 1) Locus from a parent with allele without mutation or recombination, (or with recombination between another parent with allele ). 2) Locus from a parent with allele following an to mutation but no recombination (or with recombination between another parent with allele ). 3) Locus from a parent with allele without mutation, but with recombination between another parent with allele . 4) Locus from a parent with allele following an to mutation and recombination between another parent with allele . An offspring with allele can be derived from parent(s) in four pathways similar to those described above. For the purpose of illustration, only 8 genomes were presented in generation -1 and .<p><b>Copyright information:</b></p><p>Taken from "Selection dramatically reduces effective population size in HIV-1 infection"</p><p>http://www.biomedcentral.com/1471-2148/8/133</p><p>BMC Evolutionary Biology 2008;8():133-133.</p><p>Published online 3 May 2008</p><p>PMCID:PMC2396635.</p><p></p
