Y) are arranged in a circle (blue line). Red lines connect the genomic map positions of the members in each subfamily: (A) JAK, Janus kinase; (B) SOS, son of sevenless homolog; (C) SHC, SHC (Src homology 2 domain containing)-transforming protein; and (D) VAV, oncogene. Gray lines connect the genomic map positions of the genes in each BV paralogous pair (a paralogous pair that were formed at the Base of the Vertebrate lineage) of paralogons. Additional File contains the genomic maps of all AIS subfamilies.<p><b>Copyright information:</b></p><p>Taken from "Expansion of signaling genes for adaptive immune system evolution in early vertebrates"</p><p>http://www.biomedcentral.com/1471-2164/9/218</p><p>BMC Genomics 2008;9():218-218.</p><p>Published online 14 May 2008</p><p>PMCID:PMC2391169.</p><p></p
