MEFs of the indicated genotypes were irradiated at the indicated doses and harvested 1 h later (A) or irradiated (2 Gy) and harvested at different time points (B). Cell extracts were then blotted with the indicated antibodies. (C) MEFs were left untreated or irradiated (2 Gy). 1 h later, cells were stained for antiphospho-H3 antibodies, and mitotic populations were determined by FACS. Error bars represent SEM.<p><b>Copyright information:</b></p><p>Taken from "Distinct versus overlapping functions of MDC1 and 53BP1 in DNA damage response and tumorigenesis"</p><p></p><p>The Journal of Cell Biology 2008;181(5):727-735.</p><p>Published online 2 Jun 2008</p><p>PMCID:PMC2396806.</p><p></p
