M, DNA marker. (B) WT, , 5, and 5 MEFs were treated with 1 μg/ml of untreated or RNase III–treated poly I:C for 16 h. The production of IFN-β in the supernatant was measured by ELISA. mock, no RNA. (C) Relative induction of IFN-β after stimulation with poly I:C treated with RNase III for the indicated periods. (D) The production level of IFN-β in the stimulation with RNase A–treated, Bal31-treated, or alkaline-hydrolyzed poly I:C. Error bars show the SDs between triplicates.<p><b>Copyright information:</b></p><p>Taken from "Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5"</p><p></p><p>The Journal of Experimental Medicine 2008;205(7):1601-1610.</p><p>Published online 7 Jul 2008</p><p>PMCID:PMC2442638.</p><p></p
