Performance on PROSITE true positives, false positives, and false negative test sites

Abstract

We show the true positive (TP), false negative (FN), and false positive (FP) prediction rates for SeqFEATURE (at 95%, 99%, and 100% specificity) and PROSITE on test sites derived from the corresponding PROSITE patterns. The PROSITE values represent the maximum possible for each category. Not all patterns had a false negative or false positive test set. Most of SeqFEATURE's incorrect predictions at 95% and 99% specificity cutoffs arise from poor performance on a small subset of the patterns.<p><b>Copyright information:</b></p><p>Taken from "The SeqFEATURE library of 3D functional site models: comparison to existing methods and applications to protein function annotation"</p><p>http://genomebiology.com/content/9/1/R8</p><p>Genome Biology 2008;9(1):R8-R8.</p><p>Published online 16 Jan 2008</p><p>PMCID:PMC2395245.</p><p></p

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