The severity of malarial anaemia in infections of BALB/c mice is determined independently of the number of circulating parasites-1

Abstract

Er of circulating parasites and d) % of pRBC over the same time scale in AS-infected mice (black circle), CB-infected mice (open circle) and naive control animals (-). For each day the circles in a) to d) represent the average and the error bars the standard error of the mean (SEM) of 5 animals from experiment 2. e) and f) residual number of circulating RBCs after experiment and clone have been taken into consideration plotted against peak percentage parasitemia (e) or peak number of pRBC (f) for all three experiments. Each symbol represents the values for a single mouse infected with clone AS (black circle) or clone CB (open circle). The solid lines represent the best fit linear regression line in each case, and the dashed lines highlight the residual anaemia observed once the data is normalized for experimental and clonal variation in the magnitude of RBC loss (ANOVA model "RBC loss = experiment+clone").<p><b>Copyright information:</b></p><p>Taken from "The severity of malarial anaemia in infections of BALB/c mice is determined independently of the number of circulating parasites"</p><p>http://www.malariajournal.com/content/7/1/68</p><p>Malaria Journal 2008;7():68-68.</p><p>Published online 25 Apr 2008</p><p>PMCID:PMC2412895.</p><p></p

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