Immunohistofluorescence analyses for tumor necrosis factor receptor superfamily member 1a (TNFR1a), tumor necrosis factor receptor type 1, associated death domain (TRADD), Caspase 3, and c-fos to fluorogold-traced retinas in naïve, intraorbital nerve transection (IONT) and intraorbital nerve crush (IONC) injured retinas. Expression pattern of TNFR1a (red signal) in naïve retinas (, right), IONT-injured retinas (, right) and IONC-injured retinas (, right). Left images are the corresponding fluorogold (FG) images (blue signal). Expression pattern of TRADD (red signal) in naïve retinas (, right), IONT-injured retinas (, right) and IONC-injured retinas (, right). Left images are the corresponding fluorogold (FG) images (blue signal). Expression pattern of Caspase 3 (red signal) in naïve retinas (, right), IONT-injured retinas (, right) and IONC-injured retinas (, right). Left images are the corresponding fluorogold (FG) images (blue signal). Expression pattern of c-fos (red signal) in naïve retinas (, right), IONT-injured retinas (, right) and IONC-injured retinas (, right). Left images are the corresponding fluorogold (FG) images (blue signal). Magnifications in squares show the co-localization of a given protein with FG-labeled retinal ganglion cells (RGCs). Arrows point to RGC, arrowheads indicate the outer nuclear layer and asterisks mark the nerve layer.<p><b>Copyright information:</b></p><p>Taken from "Time course profiling of the retinal transcriptome after optic nerve transection and optic nerve crush"</p><p></p><p>Molecular Vision 2008;14():1050-1063.</p><p>Published online 03 Jun 2008</p><p>PMCID:PMC2426719.</p><p></p
