(A and B) Normalized relationships from oocytes expressing (A) Kv1.2-R294H-D352H ( = 7) and (B) Kv1.2-D352H ( = 7) channels recorded in the absence (solid squares) and presence (open circles) of 1 μM Zn. (C) A plot of ΔV versus Zn concentration in oocytes expressing Kv1.2-R294H-D352H channels, where ΔV is the difference between the fitted V values obtained in the absence and presence of varying concentrations of Zn. The data were fitted with a hyperbolic function (solid curve) with a half-maximal concentration of 470 nM ( = 5–10).<p><b>Copyright information:</b></p><p>Taken from "Atomic Constraints between the Voltage Sensor and the Pore Domain in a Voltage-gated K Channel of Known Structure"</p><p></p><p>The Journal of General Physiology 2008;131(6):549-561.</p><p>Published online Jan 2008</p><p>PMCID:PMC2391244.</p><p></p
