Comparison of plasma levels of biomarkers of disordered coagulation and fibrinolysis in 50 patients with acute lung injury and acute respiratory distress syndrome ventilated with low-tidal-volume ventilation. Plasma levels of protein C were significantly lower in nonsurvivors compared with survivors. Plasma levels of thrombomodulin were significantly higher in nonsurvivors compared with survivors. Plasma levels of plasminogen activator inhibitor 1 (PAI-1) were significantly higher in nonsurvivors compared with survivors. Data shown as boxplots: horizontal line, median; box, 25th to 75th percentiles; error bars, 10th to 90th percentiles. *= 0.0003, **= 0.005 and = 0.01 compared with survivors, Mann–Whitney U test.<p><b>Copyright information:</b></p><p>Taken from "Biomarkers of inflammation, coagulation and fibrinolysis predict mortality in acute lung injury"</p><p>http://ccforum.com/content/12/2/R41</p><p>Critical Care 2008;12(2):R41-R41.</p><p>Published online 21 Mar 2008</p><p>PMCID:PMC2447583.</p><p></p
