) were detected using a polyclonal rabbit anti human TF antibody. Effect of sTF injected into the footpad: 1 μg sTF (in 10 μl phosphate-buffered saline) was injected into the intraplantar region of the right hindfootpad. The contralateral footpad was injected with the same volume of phosphate-buffered saline. Swelling was observed in the sTF-injected footpad after 2 hours and was sustained over 24 hours (photograph). Dose-dependent effect of sTF-induced inflammation: 0.2 to 5 μg sTF in 10 μl was administered into the hindfootpad. The contralateral footpad was injected with phosphate-buffered saline. Results expressed as the percentage increase in the right over left footpad thickness. *< 0.05, **< 0.01 and ***< 0.001, Wilcoxon rank sum test.<p><b>Copyright information:</b></p><p>Taken from "Essential role of platelet activation via protease activated receptor 4 in tissue factor-initiated inflammation"</p><p>http://arthritis-research.com/content/10/2/R42</p><p>Arthritis Research & Therapy 2008;10(2):R42-R42.</p><p>Published online 15 Apr 2008</p><p>PMCID:PMC2453761.</p><p></p
